In vitro Permeability
- PAMPA
- Caco-2
- MDCK (wild type)
Animal Pharmacokinetics
Pharmacokinetics by routes viz., oral, intravenous, intraperitoneal, subcutaneous in mice rats etc
- Tissue Distribution
- Brain to Plasma Ratio
- Biliary Excretion
- Mass Balance
Physicochemical properties
- Solubility (Thermodynamic and Kinetic method)
- Log D (Octanol/water and Cyclohexane/water)
- Chemical Stability
- Blood Partitioning